We understand it’s not all work, all the time. After all, we have families, too. That’s why you’ll find perks and policies designed to let you enjoy your life as much as you enjoy your career.
More than your skill and your talent, your potential is the most important thing about you. And we recognize that, by consistently providing opportunities for advancement.
Your work here is as meaningful to us as it is to you. That’s why we’re looking for people who don’t want to simply make a paycheck, they want to make a difference. Does this sound like you? If so, we should be talking.
Collaboration is more than simply working together—it’s about building on each other’s thinking and working with a shared purpose. Here, collaboration happens every day.
We foster a culture of inclusion and equality to provide a safe place for all in which to work and thrive. Join us. Be you.
We offer incentives, recognition programs and more, to ensure valuable work is met with the reward it deserves.
Plumino Precision Fermentation USA, Inc. is a leader in the biotechnology industry dedicated to supplying our customers with the highest-quality products.
Our highly sophisticated production facility utilizes advanced technology and strict quality control standards to produce the highest quality amino acids for nutraceutical, cosmeceutical, and pharmaceutical applications.
Plumino actively contributes to the health and well-being of people around the world, and to the local community as well.
Plumino is a leading biochemical manufacturer located in Southeast Missouri producing high grade premium amino acids that are used in the food and pharmaceutical industry. We strive to contribute to the health and well-being of people around the world by creating new value through the pursuit of advances of life sciences and technologies.
Position Summary:
The Research Assistant will work with in a creative and diverse Technical department in continued efforts to improve processes and equipment for optimum production output and product quality. The work is project-based with a responsibility to provide meaningful data, conclusions, and recommendations for process improvements.
Hours:
Base work schedule is Monday thru Friday, 8 am - 4:30 pm with overtime as needed for business necessity. Evenings and weekends may be necessary on occasion due to project needs.
Hourly wage is based on experience and education, up to $26.51 maximum rate. Plumino offers an excellent benefit package including medical, prescription drug and dental insurance, FSA/HSA, life and disability insurance, 401k match and profit sharing, vacation and sick leave time.
Position Requirements:
Preferred Attributes:
General Job Duties:
Quality Requirements:
Minimal facial hair, minimal makeup, no jewelry, false fingernails, nail polish, hair extensions, wigs, toupees, cologne or perfume. Long hair must be tied up for safety reasons. Facility is a non-smoking, non-tobacco facility.
Plumino is a leading biochemical manufacturer located in Southeast Missouri producing high grade premium amino acids that are used in food and pharmaceutical industry. We strive to contribute to the health and well-being of people around the world by creating new value through the pursuit of advances of life sciences and technologies.
Position Summary:
Entry level operators can begin in packaging or production fermentation or extraction field operations based on experience and business needs at time of hiring. Operators will run equipment and perform tasks as per SOP’s and production needs.
Hours:
Base work schedule is a 12-hour shift rotation, working 2 weeks of days then 2 weeks of nights, 36-hour week followed by 48-hour week, averaging only 14 days per month.
Starting wage will range from $20.91 - $24.13 depending on position, with an increase after 90 days of successful performance, paid weekly. Plumino offers an excellent benefit package including affordable health and dental insurance, FSA or HSA, life and disability insurance, 401k match and profit sharing, vacation and sick leave time.
Position Requirements:
General Job Duties (dependent on position):
Environmental Demands
Able to hear and respond to the overhead paging and alarm system; available for overtime and call-ins as needed. Production facility is subject to extremes in temperature and loud machinery noises which requires hearing protection. Some regular work in high places and confined spaces. Various chemical products used in working areas and in facility.
Quality Requirements:
Minimal facial hair, minimal makeup, no jewelry, false fingernails, nail polish, hair extensions, wigs, toupees, cologne or perfume. Long hair must be tied up for safety reasons. Facility is a non-smoking, non-tobacco facility.
Plumino is a leading biochemical manufacturer located in Southeast Missouri producing high grade premium amino acids that are used in the food and pharmaceutical industry. We strive to contribute to the health and well-being of people around the world by creating new value through the pursuit of advances of life sciences and technologies.
Position Summary:
QC Lab Analyst is responsible for performing routine analysis and testing using wet chemistry and sterile techniques. Responsible for accurate make-up of reagents, standards, and trace ingredients; collection and recording of data; microbial testing; use of industrial lab equipment. Position is responsible for cGMP, HACCP, ISO and other strict quality and safety guidelines.
Hours:
Position starts on 8-hour days for training purposes; will transition to 12-hour rotating shift position with potential for overtime. Rotation is 2 weeks on days, then 2 weeks on nights, rotating a 36-hour week and 48-hour week.
Starting wage is $20.96 per hour with an increase after 90 days of successful performance. Excellent benefit package includes health and dental insurance, FSA, HSA, Life and Disability insurance, 401k match and profit sharing, vacation, sick benefit time.
Position Requirements:
General Job Duties:
Physical Demands:
Ability to work efficiently unsupervised for prolonged periods; able to remain in stationary position while conducting tests. Must be able to move long distances between buildings, occasionally ascend/descend stairs, ladders, or work atop platforms 20% of time. Occasionally move or position objects and/or boxes up to 50 pounds to various areas. Must be able to detect overhead paging and alarm systems with ability to express oneself and exchange information professionally.
Quality Requirements:
Minimal facial hair, minimal makeup, no jewelry, false fingernails, nail polish, hair extensions, wigs, toupees, cologne or perfume. Long hair must be tied up for safety reasons. Facility is a non-smoking, non-tobacco facility.
Plumino is a leading biochemical manufacturer located in Southeast Missouri producing high grade premium amino acids that are used in the food and pharmaceutical industry. We strive to contribute to the health and well-being of people around the world by creating new value through the pursuit of advances of life sciences and technologies.
Position Summary:
Maintenance Technician is a team member responsible for the maintenance and repair of mechanical, pneumatic, hydraulic, production equipment including tanks, pits, buildings, and facility issues.
Hours:
Base work schedule is Monday thru Friday, 7 am - 3:30 pm with overtime as needed for business necessity. Evenings and weekends may be necessary due to business needs. Will carry pager about one weekend per month.
Wage is $28.43 per hour. Plumino offers an excellent benefit package including medical, prescription drug and dental insurance, FSA/HSA, life and disability insurance, 401k match and profit sharing, vacation and sick leave time.
Position Requirements:
General Job Duties:
Quality Requirements:
Minimal facial hair, minimal makeup, no jewelry, false fingernails, nail polish, hair extensions, wigs, toupees, cologne or perfume. Long hair must be tied up for safety reasons. Facility is a non-smoking, non-tobacco facility.
We are very grateful to the support of local community and many outstanding employees for being able to continue our business in Cape Girardeau.
~ Patrick Feeney, Chief Operating Officer
Plumino Precision Fermentation USA, Inc., formerly known as BioKyowa, has been a cornerstone of Missouri’s biotechnology landscape for more than four decades. Established in 1982, BioKyowa represented the first major plant investment by a Japanese company in the state of Missouri. When production began in 1984, it became the first commercial Lysine-producing facility in the United States, supplying feed supplements for the swine and poultry industries.
Over the years, BioKyowa evolved from a single-product, feed-grade operation into a multi-plant facility producing high-quality amino acids through advanced biotechnology. Its products found applications in nutritional supplements, cosmetics, pharmaceuticals, and other life science fields.
In 2025, the company entered a new era as Plumino Precision Fermentation USA, Inc., following Plumino’s acquisition of the pharmaceutical, food, and feed-grade amino acid and Human Milk Oligosaccharide (HMO) businesses and related assets from Kyowa Hakko Bio Co., Ltd.
Building on more than 70 years of biotechnology expertise pioneered by Kyowa Hakko Bio—whose origins trace back to the Biochemical Division of Kyowa Hakko Kogyo Co., Ltd., founded in 1949—Plumino continues a legacy of excellence in amino acid fermentation technology.
Today, Plumino Precision Fermentation USA, Inc. carries forward that pioneering spirit, driving innovation in biotechnology and amino acid research while expanding the frontiers of life science. With deep scientific roots and a forward-looking vision, Plumino is poised to shape the next generation of precision fermentation technologies for a healthier, more sustainable world.

Need more information?
Address : 5469 Nash Road
PO Box 1550
Cape Girardeau, MO 63702-1550
Email : jobs@plumino-us.com
Phone : 573.335.4849